Hiccup is described as the sudden involuntary contraction of the diaphragm, and the intercostal muscles followed by the immediate closure of the glottis. Corticosteroids, benzodiazepines, and antibiotics may cause drug-induced hiccups. Dopamine agonist-induced hiccups were reported in patients diagnosed with Parkinson's Disease (PD) in small number of cases. Here we report a patient diagnosed with PD who had severe hiccups with the use of two dopamine agonists in treatment, however hiccup was not reported with the use of Levodopa. This information may help to manage the treatment of PD, and avoid the unnecessary diagnostic procedures.
Keywords: Hiccup; Parkinson’s disease; dopamine agonist; levodopa.
Copyright: © 2019 Turkish Neuropsychiatric Society.
Conflicts of interest: The authors have no conflict of interest to declare.
Lertxundi U, Marquínez AC, Domingo-Echaburu S, Solinís MÁ, Calvo B, Del Pozo-Rodríguez A, García M, Aguirre C, Isla A. Lertxundi U, et al. Eur J Clin Pharmacol. 2017 Sep;73(9):1159-1164. doi: 10.1007/s00228-017-2275-6. Epub 2017 Jun 9. Eur J Clin Pharmacol. 2017. PMID: 28600702 Review.
Miyaoka H, Kamijima K. Miyaoka H, et al. Pharmacopsychiatry. 1999 Mar;32(2):81. doi: 10.1055/s-2007-979198. Pharmacopsychiatry. 1999. PMID: 10333169
Stacey SK, Bassett MS. Stacey SK, et al. Cureus. 2024 Jan 27;16(1):e53045. doi: 10.7759/cureus.53045. eCollection 2024 Jan. Cureus. 2024. PMID: 38410321 Free PMC article.
Mathew J, Shen S, Liu H. Mathew J, et al. Transl Perioper Pain Med. 2020;7(1):145-151. doi: 10.31480/2330-4871/103. Epub 2019 Oct 14. Transl Perioper Pain Med. 2020. PMID: 33869664 Free PMC article.
Nausheen F, Mohsin H, Lakhan SE. Nausheen F, et al. Springerplus. 2016 Aug 17;5(1):1357. doi: 10.1186/s40064-016-3034-3. eCollection 2016. Springerplus. 2016. PMID: 27588250 Free PMC article. Review.
Waack A, Maddens ME, Maddens NJ, Kuhlman A, Staudt MD. Waack A, et al. Case Rep Neurol. 2023 Jun 23;15(1):153-162. doi: 10.1159/000531570. eCollection 2023 Jan-Dec. Case Rep Neurol. 2023. PMID: 37901131 Free PMC article.
Metta V, Chung-Faye G, Ts Benamer H, Mrudula R, Goyal V, Falup-Pecurariu C, Muralidharan N, Deepak D, Abdulraheem M, Borgohain R, Chaudhuri KR. Metta V, et al. J Pers Med. 2023 Apr 23;13(5):711. doi: 10.3390/jpm13050711. J Pers Med. 2023. PMID: 37240881 Free PMC article. Review.